Derive hotspot bin position from a CN matrix

Returns the 1-based bin index of the genomic region most likely to be the BFB hotspot, defined as the bin with the highest CN variance across cells. This is data-driven and removes the need for the caller to supply pos.

Usage

derive_hotspot_pos(cna_matrix)

Arguments

cna_matrix

Numeric matrix (cells x bins).

Value

Integer bin index.