Run a single ABC simulation and compute distance to observed data

Run a single ABC simulation and compute distance to observed data

Usage

run_ABC(cna_data, allele, chromosome, params, pos = NULL, bin_length = NULL)

Arguments

cna_data

Observed CNA data frame (cell_id, chr, start, end, CN, A, B).

allele

Allele column to use ("A", "B", or "CN").

chromosome

Chromosome name as it appears in cna_data$chr (e.g. "7").

params

Named list of simulation parameters from sample_priors().

pos

Optional integer bin index for the BFB hotspot. Derived automatically from the observed data if NULL (default).

bin_length

Optional bin size in bp. Inferred from observed data if NULL.

Value

Named list with distance components and the parameter set used.